Acetyl Tetrapeptide-5 Cas 820959-17-9
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Chemical Name: Acetyl Tetrapeptide-5
Other Name: N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine; Acetyl Tetrapeptide
CAS No.: 820959-17-9
Molecular Fomula: C20H28N8O7
Molecular weight: 492.49
Appearance: White crystalline powder
Assay：≥95.0%
Acetyl Tetrapeptide-5 (CAS 820959-17-9): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
CAS No.: 820959-17-9
Molecular Formula: C20H28N8O7
Molecular Weight: 492.49 g/mol
Synonyms: Eyeseryl, Depuffin, Ac-βAla-His-Ser-His-OH
Key Parameters
| Parameter | Specification |
|---|---|
| Purity (HPLC) | ≥98.0% |
| Appearance | White to off-white powder |
| Water Content | ≤8.0% |
| Storage | -20°C (lyophilized, protected from light) |
2. Key Applications
- Anti-Edema Formulations: Reduces periorbital puffiness by inhibiting angiotensin-converting enzyme (ACE-1) and improving microcirculation.
- Anti-Aging Skincare: Enhances skin elasticity through glycation inhibition and SOD activity enhancement.
- Ocular Care Products: Clinically proven to diminish dark circles and under-eye bags in professional-grade eye creams.
3. Mechanism of Action
- Inhibits ACE-1 to regulate vascular pressure and reduce capillary leakage
- Blocks advanced glycation end-products (AGEs) formation via anti-glycation activity
- Enhances superoxide dismutase (SOD) activity for antioxidant protection
4. Usage Guidelines
Recommended Dosage: 0.005–0.05% in final formulations
Compatibility: Stable in pH 5–7 systems; add at final production stage
Formulation Types: Gels, serums, eye contour creams, anti-aging masks
5. Industry Use Cases
Case 1: Premium Eye Cream Development
A European skincare brand incorporated 0.03% Acetyl Tetrapeptide-5 into their award-winning eye cream, achieving 37% reduction in puffiness (4-week clinical trial).
Case 2: Professional Anti-Aging Line
A US cosmeceutical company utilized this peptide in their neck firming serum, demonstrating 29% improvement in skin elasticity metrics.
6. Contact for Technical Inquiry
For formulation support, bulk pricing, or clinical data:
Email: info@vivalr.com
Tel: (86) 15866781826
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