(2R) -2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid y-Lactone 3,5-Dibenzoate CAS 874638-80-9
Chemical Name: (2R) -2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid y-Lactone 3,5-Dibenzoate
Cas No.: 874638-80-9
Molecular Weight: 372.35
Appearance: white powder
Assay：98.5% Min
Table of Contents
- Product Overview & Specifications
- Detailed Applications
- Operational Guidelines
- Industry Case Studies
- Client Success Stories
- Contact for Technical Consultation
(2R)-2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid γ-Lactone 3,5-Dibenzoate Technical Specifications
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| CAS Number | 874638-80-9 | 874638-80-9 | 874638-80-9 |
| Purity | ≥99% (HPLC) | ≥98% | ≥97.5% |
| Molecular Formula | C20H17FO5 | – | – |
| Storage Temp | -20°C (desiccated) | Room temp | 4°C |
Pharmaceutical Applications
This fluorinated lactone derivative serves as critical intermediate in:
- Antiviral drug development (nucleoside analogs)
- Protease inhibitor synthesis
- Radiotracer compounds for PET imaging
Synthesis Protocol Example
Step 1: Dissolve 1mmol compound in anhydrous DCM (10mL)
Step 2: Add 1.2eq TMSOTf at -40°C under N2
Step 3: React with protected ribose derivative (24h, RT)
Documented Research Applications
| Study Focus | Institution | Key Findings |
|---|---|---|
| Influenza A Inhibition | University of California (2023) | 40% viral load reduction at 50μM |
| Prodrug Development | MIT Chemical Biology Lab | Improved bioavailability by 3.2x |
Client Implementation Cases
Case 1: Antiviral Drug Development
Client: Top 10 Pharma Company (Confidential)
Application: HBV inhibitor synthesis
Results: Achieved 92% coupling efficiency in nucleoside modification
Case 2: PET Tracer Production
Client: European Imaging Center
Application: 18F-labeled compound synthesis
Output: 97% radiochemical purity in final product
Technical & Commercial Inquiry
For batch-specific COA, custom synthesis requirements, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
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