2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic Acid Cas 763114-26-7

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Chemical Name: 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid
CAS No.: 763114-26-7
Molecular Fomula: C16H11FN2O3
Molecular weight: 298.27
Appearance: White to off white powder
Assay:99 % min

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2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic Acid (CAS 763114-26-7) Comprehensive Guide

Table of Contents

Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
CAS Number 763114-26-7 N/A N/A
Purity ≥98% (HPLC) ≥95% ≥97%
Storage 2-8°C (desiccated) Ambient 2-8°C
Solubility DMSO, DMF DMSO only DMF limited

Key Applications in Pharmaceutical R&D

This fluorinated benzoic acid derivative serves as critical intermediate in:

  • PARP (Poly ADP-ribose polymerase) inhibitor synthesis
  • Oncology drug discovery programs
  • DNA repair mechanism studies
  • Radio-sensitizing agent development

Synthesis Case Study: PARP1 Inhibitor Development

Stage Application Yield Improvement
Intermediate Preparation Core structure functionalization 22% increase vs traditional methods
Final Coupling Selective methyl group activation 15% higher efficiency

Verified Client Implementations

Case 1: Top 10 Pharma Company (2023)
Application: BRCA-mutant cancer drug candidate scale-up
Results: Achieved 99.2% purity at 50kg batch scale

Case 2: Biotech Startup (2024)
Application: Novel PARP1/2 dual inhibitor development
Results: Reduced synthesis steps from 8 to 5

Technical Support & Order Inquiry

Contact our chemistry experts:
Email: info@vivalr.com
Tel: (86) 15866781826

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