Tripropyl orthoformate CAS 621-76-1

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Chemical Name: Tripropyl orthoformate
CAS No.: 621-76-1
Molecular Fomula: C10H22O3
Molecular weight: 190.28
Appearance: Transparent colorless liquid
Assay: 98 % min

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Tripropyl Orthoformate (CAS 621-76-1) Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Parameter Tripropyl Orthoformate Typical Industry Standards
CAS Number 621-76-1 N/A
Molecular Formula C10H22O3
Purity Grade ≥99% (Industrial Grade) ≥95%
Boiling Point 220-222°C 215-225°C
Flash Point 96°C 90-100°C
Storage Requirements 2-8°C in airtight containers Ambient temperature

2. Key Applications & Industry Uses

Primary Functional Uses:

  • Pharmaceutical intermediates synthesis
  • Protecting group in organic reactions
  • Crosslinking agent for specialty polymers
  • Solvent for high-temperature reactions

Industry-Specific Applications:

  • API manufacturing for antiviral medications
  • Production of heat-resistant epoxy resins
  • Electrolyte additive in lithium-ion batteries

3. Performance Comparison

Feature Tripropyl Orthoformate Trimethyl Orthoformate Triethyl Orthoformate
Reaction Efficiency 92-95% 85-88% 89-91%
Thermal Stability Up to 250°C 200°C 230°C
Solubility in Ethanol Complete Partial Complete

4. Operational Guidelines

Pharmaceutical Intermediate Synthesis:

  1. Charge reactor with 1.2 molar equivalents
  2. Maintain nitrogen atmosphere throughout
  3. Gradual temperature ramp to 80°C over 90min

Polymer Crosslinking Process:

  1. Pre-mix with resin base at 3:1 ratio
  2. Catalyze with 0.5% tin-based catalyst
  3. Cure at 120°C for 45 minutes

5. Client Success Stories

Case 1: Shanghai PharmaTech Co., Ltd.

  • Application: Remdesivir intermediate production
  • Result: 18% yield improvement vs previous process
  • Throughput: 2.3MT/month continuous operation

Case 2: BASF Specialty Polymers Division

  • Application: High-Tg polyimide production
  • Outcome: Achieved V-0 flame rating at 0.8mm thickness
  • Capacity: 12MT annual consumption

6. Technical & Procurement Support

For formulation assistance or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Request customized specifications:

  • Custom purity levels (99.5%+ available)
  • Drum/Tote/IBC container options
  • GMP-grade manufacturing support
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