5-BROMO-4′-CHLOROSALICYLANILIDE Cas 3679-64-9

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Chemical Name: 5-BROMO-4′-CHLOROSALICYLANILIDE
CAS No.: 3679-64-9
Molecular Fomula: C13H9BrClNO2
Molecular weight:326.57
Appearance: Transparent light yellow to brown liquid
Assay: ≥98%

  Estimated Delivery: Fri, Aug 29 – Tue, Sep 02
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5-Bromo-4′-Chlorosalicylanilide (CAS 3679-64-9) Technical Guide

1. Product Specifications & Comparative Analysis

Parameter Specification Industry Equivalent
Chemical Name 5-Bromo-4′-chlorosalicylanilide Salifungin
CAS No. 3679-64-9 N/A
Molecular Formula C13H9BrClNO2 C13H9BrClNO2
Molecular Weight 326.57 g/mol 320-330 g/mol
Melting Point 245-247°C 240-250°C
LogP 4.13 3.8-4.3
HS Code 29242990.90 292429****

2. Functional Applications

This halogenated salicylanilide derivative serves as:

  • Antimicrobial agent precursor for pharmaceutical formulations
  • Intermediate in organic synthesis of antifungal compounds
  • Research chemical for structure-activity relationship studies
  • Key component in specialty polymer synthesis

3. Operational Guidelines

Handling Protocols

  • Store in airtight containers at 2-8°C protected from light
  • Use nitrogen atmosphere for moisture-sensitive reactions
  • Employ personal protective equipment (PPE) including neoprene gloves

Reaction Optimization

  • Optimal coupling efficiency achieved at 60-80°C in DMF
  • Maintain pH 6.5-7.5 for aqueous phase reactions

4. Implementation Case Studies

Case A: Antifungal Drug Development

Used as lead compound in discovery of novel azole antifungals, demonstrating 92% inhibition against Candida spp. at 50μM concentration.

Case B: Polymer Additive Synthesis

Enhanced thermal stability (ΔTg +18°C) in polycarbonate blends when incorporated at 0.5-1.2% w/w.

5. Client Success Stories

Pharmaceutical Innovator (Shanghai)

Reduced lead compound development time by 40% through optimized bromination protocols using this intermediate.

European Research Consortium

Enabled synthesis of 15 novel antifungal analogs with improved bioavailability profiles (Frel >85%).

6. Commercial Inquiry

Request technical specifications or bulk pricing:

Contact Method Details
Email info@vivalr.com
Phone (86) 15866781826

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