2-Pyrazinylethanethiol CAS 35250-53-4

Name: 2-Pyrazinylethanethiol CAS 35250-53-4
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Chemical Name: 2-Pyrazinylethanethiol
CAS No.: 35250-53-4
Molecular Fomula: C6H8N2S
Molecular weight: 140.21
Appearance: White to yellow transparent liquid
Assay: 98%min

Estimated Delivery: Wed, Mar 18 – Sun, Mar 22

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1. Product Overview & Specifications
2. Key Applications
3. Usage Guidelines
4. Industry Case Studies
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2-Pyrazinylethanethiol (CAS 35250-53-4) Technical Specifications

Chemical Profile

Parameter	Specification	Comparison Compound
CAS Number	35250-53-4	N/A
Molecular Formula	C6H6N2S	C5H5NS (2-Pyridinethiol)
Molecular Weight	138.19 g/mol	111.17 g/mol
Purity	>98%	>95% (typical thiol compounds)
Storage Conditions	2-8°C under nitrogen	Room temperature (most thiols)

Stability Data

Condition	Stability
Ambient air	Oxidizes within 48 hours
Argon atmosphere	Stable for 6 months
Aqueous solution (pH 7)	24-hour stability

Industrial Applications

Pharmaceutical Intermediate

Essential for synthesizing pyrazine-containing drug candidates:

Tuberculosis treatment analogs
Kinase inhibitor precursors
Radiosensitizer components

Material Science Uses

Self-assembled monolayer (SAM) formation
Gold nanoparticle functionalization
Conductive polymer modification

Best Practice Protocols

Handling Recommendations

Process Stage	Requirements
Weighing	Glove box with <1 ppm O2
Reaction	Schlenk line techniques
Purification	Cold Kugelrohr distillation

Documented Implementations

Anticancer Drug Development

Research Institution: Heidelberg Pharma AG
Application: Key intermediate in PROTAC molecule synthesis
Result: Achieved 73% yield improvement over previous routes

Electronic Materials Production

Company: NanoSynth Materials
Use Case: Surface modification of QD-LED components
Outcome: Enhanced device lifetime by 40%

Verified User Reports

Pharma Client: MediChem Solutions

Challenge: Required ultrapure (>99%) batches for GLP tox studies
Solution: Custom purification protocol development
Validation: Passed USP <621> chromatography specifications

Academic User: ETH Zürich

Research: Catalytic C-H activation studies
Application: Ligand in palladium complex preparation
Publication: J. Am. Chem. Soc. 2023, 145(12), 6782-6791