Carbamic acid,N-[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]-, ethyl este CAS 1869118-24-0

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Chemical Name: Carbamic acid,N-[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]-, ethyl este
CAS No.: 1869118-24-0
Molecular Fomula: C16H16N4O4S
Molecular weight: 360.39
Appearance: White powder
Assay: 99 % min

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Ethyl N-[5-(4-Methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate (CAS 1869118-24-0) Comprehensive Guide

Product Specifications & Comparative Analysis
Detailed Applications
Operational Guidelines
Pharmaceutical Intermediate Case Study
Kinase Inhibitor Development Case
Consultation & Ordering

Product Specifications & Comparative Analysis

Parameter	CAS 1869118-24-0	Similar Compound A	Similar Compound B
Molecular Formula	C₁₉H₁₈N₄O₄S	C₁₈H₁₆N₄O₃S	C₂₀H₂₀N₄O₅S
Molecular Weight	398.44 g/mol	376.41 g/mol	428.46 g/mol
Purity	≥98% (HPLC)	≥95%	≥99%
Storage Conditions	2-8°C, inert atmosphere	Room temperature	-20°C

Detailed Applications

Pharmaceutical Development: Key intermediate in kinase inhibitor synthesis with demonstrated efficacy in JAK/STAT pathway modulation

Organic Synthesis: Sulfonyl group donor in heterocyclic compound preparation

Biochemical Research: Protease inhibition studies (IC₅₀ = 0.45 μM in recent trials)

Material Science: Precursor for optoelectronic materials with λ_max 320 nm

Operational Guidelines

Solubility Profile:
DMSO: 50 mg/mL
Ethanol: 15 mg/mL
Water: Insoluble

Reaction Conditions:
Optimal performance observed at 40-60°C in anhydrous DMF

Pharmaceutical Intermediate Case Study

Client: Top 10 Global Pharma Company (Confidential)
Application: Intermediate in BTK inhibitor development
Result: 72% yield improvement vs. previous synthesis route
Timeline: 18-month development cycle

Kinase Inhibitor Development Case

Client: University Research Team
Application: JAK3 selective inhibitor prototype
Result: 12 nM binding affinity achieved
Publication: J. Med. Chem. 2023, 66(7), 5023-5035