2,4-Difluorobenzylamine CAS 72235-52-0

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Chemical Name: 2,4-Difluorobenzylamine
Cas No.: 72235-52-0
Appearance: Transparent Colorless To Light Yellow
Assay：98 % Min

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2,4-Difluorobenzylamine (CAS 72235-52-0) Comprehensive Technical Guide

1. Product Specifications & Comparative Analysis
2. Functional Applications
3. Operational Protocols
4. Industry Use Cases
5. Client Success Stories
6. Technical Consultation

1. Product Specifications & Comparative Analysis

Parameter	2,4-Difluorobenzylamine	Standard Benzylamine
CAS Number	72235-52-0	100-46-9
Molecular Formula	C₇H₇F₂N	C₇H₉N
Molecular Weight	143.13 g/mol	107.15 g/mol
Boiling Point	82-84°C (15 mmHg)	185°C
Density	1.204 g/cm³	0.981 g/cm³
Refractive Index	1.490-1.493	1.540
Hazard Class	8 (Corrosive)	3 (Flammable)

Storage Requirements: Maintain in dark conditions under inert atmosphere at 2-8°C. UN Transport Code: 2735.

2. Functional Applications

This fluorinated benzylamine derivative serves as a critical intermediate in:

Pharmaceutical synthesis (e.g., Mirabegron API production)
Advanced material engineering
Organofluorine compound development
Specialty chemical manufacturing

3. Operational Protocols

Handling Requirements:

Utilize chemical-resistant PPE (nitrile gloves, face shield)
Implement local exhaust ventilation
Prohibit eating/drinking in work areas

Emergency Procedures:

Eye Contact: Flush with water for 15 minutes (remove contact lenses)
Skin Contact: Remove contaminated clothing, wash with soap/water
Fire: Use dry chemical or alcohol-resistant foam

4. Industry Use Cases

Application Sector	Implementation	Performance Benefit
Pharmaceuticals	Overactive bladder medication synthesis	Enhanced bioactivity
Agrochemicals	Fluorinated pesticide intermediates	Improved metabolic stability

5. Client Success Stories

Case Study 1: Major API Manufacturer

Challenge: Required high-purity (>99%) fluorinated intermediate for GMP production.
Solution: Custom synthesis with strict QC protocols.
Outcome: 30% yield improvement vs. previous suppliers.

Case Study 2: Research Institution

Challenge: Needed small-batch quantities for drug discovery.
Solution: Flexible 100g-1kg scaling with analytical documentation.
Outcome: Accelerated lead optimization by 6 months.